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A GLP-1R agonist/GIPR antagonist peptide is theoretically possible but few full-length GIP-like antagonists were reported, 60 therefore it requires an array of attempts, at least an alanine-scan experiment of GIP with measuring of affinity

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The bioequivalence criterion was met for ethinylestradiol area under the curve (AUC 0–24 h ) for semaglutide steady-state/semaglutide-free